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Boudjemaa Hadjer

Benbouali Hassiba University of Chlef, Algeria

Title: Bioactive constituents and potential antimicrobial of essential oil of Lavandula angustifolia Mill: Other treatment against penicillin resistant bacteria and uropathogenic Candida

Biography

Biography: Boudjemaa Hadjer

Abstract

Currently, the evolution a number of infectious diseases has been indiscriminate each year, emerging and re-emerging infection bacteria resistant to antibiotics becomes a threat to the health of humanity. Medicinal plants constitute bioactive substances, the powerful weapons against multidrug resistant microbial infection. In this research, our object to detect antibacterial and antifungal potentials of the Mediterranean Lavandula angustifolia Mill (lavender oil) with its bioactive compounds, linalyl anthranilate and linalool, were determined in vitro against twelve reference and clinical penicillin resistant strain encountered in private laboratory.EO was evaluated for antimicrobial activity by minimum inhibitory concentration (MIC), bactericidal, fungicide by disc diffusion assay and agar dilution assay. The strains that showed resistance against penicillin, ampicillin and oxacillin antibiotics tested were selected for an antibacterial assay. The penicillin resistant bacteria strains were sensitive to the antimicrobial activity of EO of
Lavandula angustofolia Mill. The most inhibition zone of Lavender essential oil was related to E.coli ATCC1536 and Bacillus subtilis ATCC6133 and B. cereus ATCC10876, Micrococcus luteus, in disk diffusion in agar well diffusion method. The lowest minimum inhibitory concentration (MIC) for Lavender essential oil against E.coli ATCC1536, B. subtilis ATCC6133, M. luteus were 0.02%, 0.02%, 0.04% (v/v) respectively. The MIC value of Lavender essential oil against C. albicans, C. albicans ATCC1231 were 0.04%,
0.02% (v/v) respectively. Bactericidal activity was higher against almost all tested bacteria M. luteus, B. subtillis ATCC6133, B. cereus ATCC10876 were 0.02%; mean minimum fungicide concentration (MFC) of C. albicans, C. albicans ATCC1231 0.1%, 0.01% (v/v)respectively. The composition of bioactive molecule of EO was analyzed by gas chromatography mass spectrometry showing terpene alcohol as dominant constituent. Lavender essential oil is strong potential microbicide against the tested bacterial and fungal human pathogens strains.