Applied Microbiology

Transplantation Immunology

Transplantation refers to transfer of living cells, tissues and organs from one part of the body to another from one individual to another. Transplantation mainly consists of three types: (1) organ or tissue transplantation; (2) Anatomical site of origin of transplant & site of its placement i.e., orthotropic (normal sites), heterotopic (abnormal sites); (3) Vital grafts and Structural grafts. The roles of the different components of the immune system involved in the tolerance or rejection of grafts and in graft-versus-host disease have been clarified. These elements consist of counteract ant, ant generative cells, helper and cytotoxic T cell subsets, immune cell surface molecules, signaling mechanisms and cytokines that they release.